Structure of PDB 6nvq Chain C

Receptor sequence
>6nvqC (length=244) Species: 9606 (Homo sapiens) [Search protein sequence]
FVNRGGLPVDEATWERMWKHVAKIHPDGEKVAQRIRGATDLPKIPIPSVP
TFQPSTPVPERLEAVQRYIRELQYNHTGTQFFEIKKSRPLTGLMDLAKEM
TKEALPIKALEAVILGIYLTNSMPTLERFPISFKTYFSGNYFRHIVLGVN
FAGRYGALGMSRREDLMYKPPAFRTLSELVLDFEAAYGRCWHVLKKVKLG
QSVSHDPHSVEQIEWKHSVLDVERLGRDDFRKELERHARDMRLK
3D structure
PDB6nvq Crystal structure of the tubulin tyrosine carboxypeptidase complex VASH1-SVBP.
ChainC
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.17.17: tubulinyl-Tyr carboxypeptidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide C P68 V69 W74 V81 H85 I95 R96 G97 I104 P105 I106 L132 Y134 H136 F141 E163 A164 L165 P166 P8 V9 W14 V21 H25 I35 R36 G37 I44 P45 I46 L72 Y74 H76 F81 E103 A104 L105 P106
Gene Ontology
Biological Process
GO:0045765 regulation of angiogenesis
Cellular Component
GO:0005737 cytoplasm

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Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6nvq, PDBe:6nvq, PDBj:6nvq
PDBsum6nvq
PubMed31270470
UniProtQ7L8A9|VASH1_HUMAN Tubulinyl-Tyr carboxypeptidase 1 (Gene Name=VASH1)

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