Structure of PDB 6nqa Chain C

Receptor sequence
>6nqaC (length=106) Species: 8355 (Xenopus laevis) [Search protein sequence]
AKAKTRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAE
ILELAGNAARDNKKTRIIPRHLQLAVRNDEELNKLLGRVTIAQGGVLPNI
QSVLLP
3D structure
PDB6nqa Mechanism of Cross-talk between H2B Ubiquitination and H3 Methylation by Dot1L.
ChainC
Resolution3.54 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna C K15 T16 R17 R20 R32 R77 K4 T5 R6 R9 R21 R66
BS02 dna C R42 V43 A45 K75 T76 R77 R31 V32 A34 K64 T65 R66
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005694 chromosome

View graph for
Molecular Function

View graph for
Cellular Component
External links
PDB RCSB:6nqa, PDBe:6nqa, PDBj:6nqa
PDBsum6nqa
PubMed30765112
UniProtP06897|H2A1_XENLA Histone H2A type 1

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