Structure of PDB 6n9w Chain C

Receptor sequence
>6n9wC (length=276) Species: 10760 (Escherichia phage T7) [Search protein sequence]
DGVVSALSLRERIREHLSSSVGLLFSGCTGINDKTLGARGGEVIMVTSGS
GMGKSTFVRQQALQWGTAMGKKVGLAMLQESVEETAEDLIGLHNRVRLRQ
SDSLKREIIENGKFDQWFDELFGNDTFHLYDSETDRLLAKLAYMRSGLGC
DVIILDHISIVVSASGESDERKMIDNLMTKLKGFAKSTGVVLVVICHLKN
PDKGKAHEEGRPVSITDLRGSGALRQLSDTIIALERNQMPNLVLVRILKC
RFTGDTGIAGYMEYNKETGWLEPSSY
3D structure
PDB6n9w Structures and operating principles of the replisome.
ChainC
Resolution4.0 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.7.7.-
3.6.4.12: DNA helicase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna C R439 K467 N468 G488 S489 G490 R171 K199 N200 G220 S221 G222
BS02 TTP C G315 M316 G317 K318 S319 T320 R504 Y535 G51 M52 G53 K54 S55 T56 R236 Y264
BS03 MG C S319 Q343 S55 Q79
BS04 TTP C R522 F523 T524 R251 F252 T253
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003678 DNA helicase activity
GO:0003697 single-stranded DNA binding
GO:0003896 DNA primase activity
GO:0004386 helicase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008270 zinc ion binding
GO:0016779 nucleotidyltransferase activity
GO:0016787 hydrolase activity
GO:0016887 ATP hydrolysis activity
GO:0042802 identical protein binding
GO:0043139 5'-3' DNA helicase activity
GO:0046872 metal ion binding
Biological Process
GO:0006260 DNA replication
GO:0006269 DNA replication, synthesis of primer
GO:0032508 DNA duplex unwinding
GO:0039693 viral DNA genome replication
Cellular Component
GO:1990077 primosome complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6n9w, PDBe:6n9w, PDBj:6n9w
PDBsum6n9w
PubMed30679383
UniProtP03692|HELIC_BPT7 DNA helicase/primase (Gene Name=4)

[Back to BioLiP]