Structure of PDB 6mn0 Chain C

Receptor sequence
>6mn0C (length=261) Species: 77133 (uncultured bacterium) [Search protein sequence]
SSRVSTRSSLAEDLRAIGLADGDAVLVHAALRKVGKIVGGPDDILDAMRD
VIGPAGTVLGYADWQLEDEIRDDPAMREHIPAFDPLRSRSIRDNGFWPEL
IRTTPGALRSASPGASMAAIGGEAEWFTADHALDYGYGPRSPLGKLVEAK
GKVLMLGAPLDTMTLLAHAEHLADFPNKRILRYEAPILVDGEKVWRWFEE
FDTSDPPDGLADDYFAGIVEEFLATGRGKRGKIGEASSVLVPADEIVAFA
VDWLERWGRTA
3D structure
PDB6mn0 Structural and molecular rationale for the diversification of resistance mediated by the Antibiotic_NAT family.
ChainC
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.1.81: aminoglycoside N(3)-acetyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ACO C H29 A30 A31 L32 R33 P42 Y62 N95 G96 F97 P160 T163 T165 H28 A29 A30 L31 R32 P41 Y61 N94 G95 F96 P159 T162 T164
BS02 ACO C Q66 R93 Q65 R92
Gene Ontology
Molecular Function
GO:0008080 N-acetyltransferase activity
GO:0016746 acyltransferase activity
GO:0046353 aminoglycoside 3-N-acetyltransferase activity
Biological Process
GO:0046677 response to antibiotic

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Molecular Function
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Biological Process
External links
PDB RCSB:6mn0, PDBe:6mn0, PDBj:6mn0
PDBsum6mn0
PubMed35338238
UniProtA0A059X981

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