Structure of PDB 6mii Chain C

Receptor sequence
>6miiC (length=589) Species: 273057 (Saccharolobus solfataricus P2) [Search protein sequence]
QIDYRDVFIEFLTTFKGNNNQNKYIERINELVAYRKKSLIIEFSDVLSFN
ENLAYEIINNTKIILPILEGALYDHILQLDPTYQRDIEKVHVRIVGIPRV
IELRKIRSTDIGKLITIDGILVKVTPVKERIYKATYKHIHPDCMQEFEWP
EDEEMPEVLEMPTICPKCGKPGQFRLIPEKTKLIDWQKAVIQERPEEVPS
GQLPRQLEIILEDDLVDSARPGDRVKVTGILDIKQDSPVKRGSRAVFDIY
MKVSSIEVSSEEDEKKIKDLAKDPWIRDRIISSIAPSIYGHWELKEALAL
ALFGGVPKVLEDTRIRGDIHILIIGDPGTAKSQMLQFISRVAPRAVYTTG
KGSTAAGLTAAVVREKGTGEYYLEAGALVLADGGIAVIDEIDKMRDEDRV
AIHEAMEQQTVSIAKAGIVAKLNARAAVIAAGNPKFGRYISERPVSDNIN
LPPTILSRFDLIFILKDQPGEQDRELANYILDVHSGKSTKNIIDIDTLRK
YIAYARKYVTPKITSEAKNLITDFFVEMRKKSSETPDSPILITPRQLEAL
IRISEAYAKMALKAEVTREDAERAINIMRLFLESVGVDM
3D structure
PDB6mii DNA translocation mechanism of the MCM complex and implications for replication initiation.
ChainC
Resolution3.15 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.4.12: DNA helicase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna C T369 V377 T354 V362
BS02 08T C E422 R473 P559 R560 E563 E407 R458 P544 R545 E548
BS03 08T C I303 Y304 G343 T344 A345 K346 S347 Q348 N448 I288 Y289 G328 T329 A330 K331 S332 Q333 N433
BS04 ZN C H144 C149 C171 C174 H138 C143 C165 C168
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
Biological Process
GO:0032508 DNA duplex unwinding

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Molecular Function
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Biological Process
External links
PDB RCSB:6mii, PDBe:6mii, PDBj:6mii
PDBsum6mii
PubMed31308367
UniProtQ9UXG1|MCM_SACS2 Minichromosome maintenance protein MCM (Gene Name=MCM)

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