Structure of PDB 6mfu Chain C

Receptor sequence
>6mfuC (length=216) Species: 235443 (Cryptococcus neoformans var. grubii H99) [Search protein sequence]
SRPINPDVVNRPLVICGPSGTGKSTLLKTLFESQPNTFGFSVSHTTRKPR
PGEENGREYHFVTKEEFMEGVGKGEFLEWAEFGGNCYGTTFAALTALHPR
RCILDIELQGVLQLKAKAPLQTPPLEPVFLFLSPPSISQLKSRLSGRGTE
TDASIRKRLDAAKEELRYAKEGKYDVYVVNDDLKVAGEKLEKVAMGWEGW
KTCGDTLPELNLAELD
3D structure
PDB6mfu Crystal structure of a Guanylate kinase from Cryptococcus neoformans var. grubii serotype A in complex with GDP and ADP
ChainC
Resolution1.6 Å
3D
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Enzymatic activity
Enzyme Commision number 2.7.4.8: guanylate kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 5GP C S44 R48 R51 Y60 E79 F83 Y88 G89 T90 D106 I107 E108 R159 S43 R47 R50 Y59 E78 F82 Y87 G88 T89 D105 I106 E107 R158
BS02 ADP C G21 G23 K24 S25 T26 R144 R148 N181 G20 G22 K23 S24 T25 R143 R147 N180
Gene Ontology
Molecular Function
GO:0004385 guanylate kinase activity
GO:0005524 ATP binding
GO:0016301 kinase activity
Biological Process
GO:0006163 purine nucleotide metabolic process
GO:0016310 phosphorylation
GO:0046037 GMP metabolic process
GO:0046710 GDP metabolic process
Cellular Component
GO:0005829 cytosol

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Cellular Component
External links
PDB RCSB:6mfu, PDBe:6mfu, PDBj:6mfu
PDBsum6mfu
PubMed
UniProtJ9VQ84

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