Structure of PDB 6mb6 Chain C

Receptor sequence
>6mb6C (length=265) Species: 287 (Pseudomonas aeruginosa) [Search protein sequence]
FATRTSLAADLAALGLAWGDAIMVHAAVSRVGRLLDGPDTIIAALRDTVG
PGGTVLAYADWEARYEDLVDDAGRVPPEWREHVPPFDPQRSRAIRDNGVL
PEFLRTTPGTLRSGNPGASLVALGAKAEWFTADHPLDYGYGEGSPLAKLV
EAGGKVLMLGAPLDTLTLLHHAEHLADIPGKRIKRIEVPFATPTGTQWRM
IEEFDTGDPIVAGLAEDYFAGIVTEFLASGQGRQGLIGAAPSVLVDAAAI
TAFGVTWLEKRFGTP
3D structure
PDB6mb6 Encoding of Promiscuity in an Aminoglycoside Acetyltransferase.
ChainC
Resolution2.25 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.3.1.81: aminoglycoside N(3)-acetyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 COA C A33 A34 V35 S36 N104 G105 V106 F110 A168 P169 T172 A26 A27 V28 S29 N97 G98 V99 F103 A161 P162 T165
Gene Ontology
Molecular Function
GO:0008080 N-acetyltransferase activity
GO:0016746 acyltransferase activity
GO:0046353 aminoglycoside 3-N-acetyltransferase activity
Biological Process
GO:0046677 response to antibiotic

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:6mb6, PDBe:6mb6, PDBj:6mb6
PDBsum6mb6
PubMed30347146
UniProtQ51405

[Back to BioLiP]