Structure of PDB 6lj3 Chain C

Receptor sequence
>6lj3C (length=140) Species: 10497 (African swine fever virus) [Search protein sequence]
ATNFFIQPITEEAEAYYPPSVITNKRKDLGVDVYCCSDLVLQPGLNIVRL
HIKVACEHMGKKCGFKIMARSSMCTHERLLILANGIGLIDPGYVGELMLK
IINLGDTPVQIWAKECLVQLVAQGDHVPDHINILKRNQIF
3D structure
PDB6lj3 Structural comparisons of host and African swine fever virus dUTPases reveal new clues for inhibitor development.
ChainC
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.1.23: dUTP diphosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 DUP C R71 S72 S73 R70 S71 S72
BS02 DUP C N85 G88 I90 D91 Y94 M99 N84 G87 I89 D90 Y93 M98
Gene Ontology
Molecular Function
GO:0004170 dUTP diphosphatase activity
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
Biological Process
GO:0009117 nucleotide metabolic process
Cellular Component
GO:0030430 host cell cytoplasm
GO:0044423 virion component

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6lj3, PDBe:6lj3, PDBj:6lj3
PDBsum6lj3
PubMed33139328
UniProtQ65199|DUTP_ASFB7 Deoxyuridine 5'-triphosphate nucleotidohydrolase (Gene Name=Ba71V-131)

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