Structure of PDB 6lbi Chain C

Receptor sequence
>6lbiC (length=84) Species: 9606 (Homo sapiens) [Search protein sequence]
AWGNLSYADLITKAIESSAEKRLTLSQIYEWMVKSVPYFKDKGDSNSSAG
WKNSIRHNLSLHSKFIRVQNEGTGKSSWWMLNPE
3D structure
PDB6lbi Mechanism of forkhead transcription factors binding to a novel palindromic DNA site.
ChainC
Resolution3.067 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna C L183 R214 H215 S218 R225 S235 W237 L25 R56 H57 S60 R67 S77 W79
BS02 dna C S164 Y165 N211 H215 S6 Y7 N53 H57
Gene Ontology
Molecular Function
GO:0003700 DNA-binding transcription factor activity
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function

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Biological Process
External links
PDB RCSB:6lbi, PDBe:6lbi, PDBj:6lbi
PDBsum6lbi
PubMed33577686
UniProtQ12778|FOXO1_HUMAN Forkhead box protein O1 (Gene Name=FOXO1)

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