Structure of PDB 6jx2 Chain C

Receptor sequence
>6jx2C (length=324) Species: 196627 (Corynebacterium glutamicum ATCC 13032) [Search protein sequence]
AIELLYDADADLSLIQGRKVAIVGYGSQGHAHSQNLRDSGVEVVIGLREG
SKSAEKAKEAGFEVKTTAEAAAWADVIMLLAPDTSQAEIFTNDIEPNLNA
GDALLFGHGLNIHFDLIKPADDIIVGMVAPKGPGHLVRRQFVDGKGVPCL
IAVDQDPTGTAQALTLSYAAAIGGARAGVIPTTFEAETVTDLFGEQAVLC
GGTEELVKVGFEVLTEAGYEPEMAYFEVLHELKLIVDLMFEGGISNMNYS
VSDTAEFGGYLSGPRVIDADTKSRMKDILTDIQDGTFTKRLIANVENGNT
ELEGLRASYNNHPIEETGAKLRDL
3D structure
PDB6jx2 Crystal Structure and Biochemical Characterization of Ketol-Acid Reductoisomerase fromCorynebacterium glutamicum.
ChainC
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.1.1.86: ketol-acid reductoisomerase (NADP(+)).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG C D192 E196 D191 E195
BS02 MG C E228 E232 E227 E231
BS03 NAP C G25 Y26 G27 S28 Q29 S52 S54 L81 P83 D84 I90 H109 P134 G24 Y25 G26 S27 Q28 S51 S53 L80 P82 D83 I89 H108 P133
BS04 MG C D192 E196 D191 E195
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0004455 ketol-acid reductoisomerase activity
GO:0008677 2-dehydropantoate 2-reductase activity
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding
GO:0050661 NADP binding
Biological Process
GO:0008652 amino acid biosynthetic process
GO:0009082 branched-chain amino acid biosynthetic process
GO:0009097 isoleucine biosynthetic process
GO:0009099 L-valine biosynthetic process
Cellular Component
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6jx2, PDBe:6jx2, PDBj:6jx2
PDBsum6jx2
PubMed31298526
UniProtQ57179|ILVC_CORGL Ketol-acid reductoisomerase (NADP(+)) (Gene Name=ilvC)

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