Structure of PDB 6jij Chain C

Receptor sequence
>6jijC (length=298) Species: 11142 (Murine hepatitis virus strain A59) [Search protein sequence]
SGIVKMVSPTSKVEPCIVSVTYGNMTLNGLWLDDKVYCPRHVICSDMTDP
DYPNLLCRVTSSDFCVMSGRMSLTVMSYQMQGCQLVLTVTLQNPNTPKYS
FGVVKPGETFTVLAAYNGRPQGAFHVTLRSSHTIKGSFLCGSCGSVGYVL
TGDSVRFVYMHQLELSTGCHTGTDFSGNFYGPYRDAQVVQLPVQDYTQTV
NVVAWLYAAIFNRCNWFVQSDSCSLEEFNVWAMTNGFSSIKADLVLDALA
SMTGVTVEQVLAAIKRLHSGFQGKQILGSCVFEDELTPSDVYQQLAGV
3D structure
PDB6jij The crystal structure of main protease from mouse hepatitis virus A59 in complex with an inhibitor.
ChainC
Resolution2.65 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.1.1.56: mRNA (guanine-N(7))-methyltransferase.
2.1.1.57: methyltransferase cap1.
2.7.7.48: RNA-directed RNA polymerase.
2.7.7.50: mRNA guanylyltransferase.
3.1.13.-
3.4.19.12: ubiquitinyl hydrolase 1.
3.4.22.-
3.6.4.12: DNA helicase.
3.6.4.13: RNA helicase.
4.6.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide C H41 F138 L139 C140 C143 H161 Q162 L163 E164 D185 Q187 V188 V189 H41 F138 L139 C140 C143 H161 Q162 L163 E164 D185 Q187 V188 V189
BS02 peptide C C140 G141 C140 G141
Gene Ontology
Molecular Function
GO:0008233 peptidase activity
Biological Process
GO:0019082 viral protein processing

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Molecular Function
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Biological Process
External links
PDB RCSB:6jij, PDBe:6jij, PDBj:6jij
PDBsum6jij
PubMed30833083
UniProtP0C6X9|R1AB_CVMA5 Replicase polyprotein 1ab (Gene Name=rep)

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