Structure of PDB 6int Chain C

Receptor sequence

>6intC (length=413) Species: 1079050 (Paenibacillus sp. R4)

YFDHVGTVKFEGKSSTNPLAFKFYNPDEIILGKTMREHLRFGVAYLSGME
LAKARVEACFELLNILDVDYFCFHDRDIAPEGDTLQETNRNLDEIVALIK
QHMHSSGKKLLWNTANMFTNPRFVHGAATTSNADVFAYAAAQVKKALDHG
KELGAENYVFWGGREGYESLLNTDLGLELDNLARFLQLAVDYAKEIGFDA
QFLIEPKPKEPSKHQYDFDAATTLQFLQKYDLAKHFKLNLEANHATLAGH
TFEHELRVARINGALGSIDANQGDLLLGWDTDEFPTDLYASTLAMYEILQ
NEGGIGRGGVNFDAKVRRTSFEPIDVVYAHINGMDAFARGLQVAAKLIED
RAFDNVIEERYASFTKGIGADIVSGKANFHTLEAYALQNNPITNKSGRVE
LLRSILNQYIINV

3D structure

• PDB: 6int Crystal Structure and Functional Characterization of a Xylose Isomerase (PbXI) from the Psychrophilic Soil Microorganism, Paenibacillus sp.
• Chain: C
• Resolution: 1.942 Å

Enzymatic activity

• Catalytic site (original residue number in PDB): H99 D102 W137 E230 K232 E266 H269 D294 D305 D307 D338
• Catalytic site (residue number reindexed from 1): H74 D77 W112 E205 K207 E241 H244 D269 D280 D282 D313
• Enzyme Commision number: 5.3.1.5: xylose isomerase.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	CA	C	E230 E266 D294 D338	E205 E241 D269 D313
BS02	CA	C	E266 H269 D305 D307	E241 H244 D280 D282
BS03	CA	C	G191 E203	G166 E178

Gene Ontology

Molecular Function

• GO:0000287 magnesium ion binding
• GO:0009045 xylose isomerase activity
• GO:0016853 isomerase activity
• GO:0046872 metal ion binding

Biological Process

• GO:0005975 carbohydrate metabolic process
• GO:0042732 D-xylose metabolic process

Cellular Component

• GO:0005737 cytoplasm

External links

• PDB: RCSB:6int, PDBe:6int, PDBj:6int
• PDBsum: 6int
• PubMed: 30602271
• UniProt: A0A4V8H014