Structure of PDB 6ica Chain C

Receptor sequence
>6icaC (length=378) Species: 272624 (Legionella pneumophila subsp. pneumophila str. Philadelphia 1) [Search protein sequence]
SPVHEQLQVPQCLAAKITVPHKILAENKEFKIIDVLSSDVETLTILADKV
SCGHFVNVSHKLTGTLAANQQQSAQKLLQKKLVKPFGVSKLHKDVYEIKH
EEEVNAALKEIVSDNIWQTLTHMTSYYNRSATKDTGVDTANWLKSKFEQM
AVEYGRTDTSTFFVKTGWYKQPSLVTVIGKDIKAPAIVIGAHMDTLDGRM
PGAGDDGSGSSSIMEAARVILSSKTTFKRPIYFIWYAAEERGLVGSQHVV
QHFQEQSIPVKAVVQFDMTGYRNDANDPTMWVFTDYTDRDLSNYLAKLID
HYIHVPVDYSRCGYGCSDHASWNEEDIPAAFPCETSFADHNPYIHTSSDK
MDLLNLEHMTNFSKLAVAFAIELASELE
3D structure
PDB6ica The crystal structure of Legionella pneumophila LapA aminopeptidase
ChainC
Resolution2.195 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) H238 D251 E285 E286 D313 H391
Catalytic site (residue number reindexed from 1) H192 D205 E239 E240 D267 H345
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN C H238 D251 D313 H192 D205 D267
BS02 ZN C D251 E286 H391 D205 E240 H345
Gene Ontology
Molecular Function
GO:0004177 aminopeptidase activity
GO:0008235 metalloexopeptidase activity
GO:0046872 metal ion binding
Biological Process
GO:0006508 proteolysis

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:6ica, PDBe:6ica, PDBj:6ica
PDBsum6ica
PubMed
UniProtQ5ZRR6

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