Structure of PDB 6i85 Chain C

Receptor sequence

>6i85C (length=399) Species: 381518 (Influenza A virus (A/Wilson-Smith/1933(H1N1)))

NATEIRASVGKMIDGIGRFYIQMCTELKLSDYEGRLIQNSLTIERMVLSA
FDTGGPIYRRVDGKWRRELILYDKEEIRRIWRQANNGDDATAGLTHMMIW
HSNLNDATYQRTRALVRTGMDPRMCSLMQGSTLPRRSGAAGAAVKGVGTM
VMELIRMIKRGINRRTRIAYERMCNILKGKFQTAAQRTMVDQVRESRNPG
NAEFEDLIFLARSALILRGSVAHKSCLPACVYGSAVASGYDFEREGYSLV
GIDPFRLLQNSQVYSLIRPNENPAHKSQLVWMACHSAAFEDLRVSSFIRG
TKVVPRGKLSTRGVQIASNENMETMESSTLELRSRYWAIRTRSGGNTSDM
RTEIIRLMESARPEDVSFQGRGVFELSDEKATSPIVPSFDMSNEGSYFF

3D structure

• PDB: 6i85 Structural insights into influenza A virus ribonucleoproteins reveal a processive helical track as transcription mechanism.
• Chain: C
• Resolution: 24.0 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	C	R162 S165 L264 I265 R267 H272 S335 F338 E339 D340 R342 I347 A387 I388 R389 T390 M448 E449 A451 R452 P453 E454 S457 F458 Q459 G460 R461 G462 P477 S486 Y487 F489	R123 S126 L215 I216 R218 H223 S286 F289 E290 D291 R293 I298 A338 I339 R340 T341 M358 E359 A361 R362 P363 E364 S367 F368 Q369 G370 R371 G372 P387 S396 Y397 F399

Gene Ontology

Molecular Function

• GO:0005198 structural molecule activity

External links

• PDB: RCSB:6i85, PDBe:6i85, PDBj:6i85
• PDBsum: 6i85
• PubMed: 32152587
• UniProt: P15682|NCAP_I33A0 Nucleoprotein (Gene Name=NP)