Structure of PDB 6hxk Chain C

Receptor sequence
>6hxkC (length=260) Species: 9606 (Homo sapiens) [Search protein sequence]
PASFMTSICDERGQELIYAGMPITEVFKEEMGIGGVLGLLWFQKRLPKYS
CQFIEMCLMVTADHGPAVSGAHNTIICARAGKDLVSSLTSGLLTIGDRFG
GALDAAAKMFSKAFDSGIIPMEFVNKMKKEGKLIMGIGHRVKSINNPDMR
VQILKDYVRQHFPATPLLDYALEVEKITTSKKPNLILNVDGLIGVAFVDM
LRNCGSFTREEADEYIDIGALNGIFVLGRSMGFIGHYLDQKRLKQGLYRH
PWDDISYVLP
3D structure
PDB6hxk Structure of ATP citrate lyase and the origin of citrate synthase in the Krebs cycle.
ChainC
Resolution1.85 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.3.8: ATP citrate synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FLC C H900 V904 F935 G936 F1061 R1065 H64 V68 F99 G100 F225 R229
Gene Ontology
Molecular Function
GO:0046912 acyltransferase activity, acyl groups converted into alkyl on transfer

View graph for
Molecular Function
External links
PDB RCSB:6hxk, PDBe:6hxk, PDBj:6hxk
PDBsum6hxk
PubMed30944476
UniProtP53396|ACLY_HUMAN ATP-citrate synthase (Gene Name=ACLY)

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