Structure of PDB 6h1b Chain C

Receptor sequence
>6h1bC (length=490) Species: 531310 (Marinactinospora thermotolerans) [Search protein sequence]
PAMGYARRVMDGIGEVAVTGAGGSVTGARLRHQVRLLAHALTEAGIPPGR
GVACLHANTWRAIALRLAVQAIGCHYVGLRPTAAVTEQARAIAAADSAAL
VFEPSVEARAADLLERVSVPVVLSLGPTSRGRDILAASVPTPLRYREHPE
GIAVVAFTSGPKGVAHSSTAMSACVDAAVSMYGRPWRFLIPIPLSDLGGE
LAQCTLATGGTVVLLEEFQPDAVLEAIERERATHVFLAPNWLYQLAEHPA
LPRSDLSSLRRVVYGGAPAVPSRVAAARERMGAVLMQNYGTQEAAFIAAL
TPDDHARRELLTAVGRPLPHVEVEIRDDSGGTLPRGAVGEVWVRSPMTMS
GYWRDPERTAQVLSGGWLRTGDVGTFDEDGHLHLTDRLQDIIIVEAYNVY
SRRVEHVLTEHPDVRAAAVVGVPDPDSGEAVCAAVVVADGADPDPEHLRA
LVRDHLGDLHVPRRVEFVRSIPVTPAGAPDKVKVRTWFTD
3D structure
PDB6h1b The Broad Aryl Acid Specificity of the Amide Bond Synthetase McbA Suggests Potential for the Biocatalytic Synthesis of Amides.
ChainC
Resolution2.8 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) T158 D201 Q297 E298 I398 N403 A483
Catalytic site (residue number reindexed from 1) T158 D196 Q292 E293 I393 N398 A478
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 AMP C G271 A272 P273 Q292 N293 Y294 G295 D377 R392 R407 G266 A267 P268 Q287 N288 Y289 G290 D372 R387 R402
BS02 EQ2 C L202 G271 N293 Y294 G295 T296 Q297 A300 F301 L197 G266 N288 Y289 G290 T291 Q292 A295 F296
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0016874 ligase activity

View graph for
Molecular Function
External links
PDB RCSB:6h1b, PDBe:6h1b, PDBj:6h1b
PDBsum6h1b
PubMed30035356
UniProtR4R1U5

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