Structure of PDB 6gys Chain C

Receptor sequence
>6gysC (length=573) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
TQLKSKHPCSVCTRRKVKCDRMIPCGNCRKRGQDSECMKSTITASSSKEY
LPDLLLFWQNYEYWITNIGLYKTKQRDLTRTPANLDTDTEECMFWMNYLQ
KDQSFQLMNFAMENLGALYFGSIGDISELYLRVEQYWDRRADKNHSVDGK
YWDALIWSVFTMCIYYMPVEKLAEIFSVYPLHEYLGSNKRLNWEDGMQLV
MCQNFARCSLFQLKQCDFMAHPDIRLVQAYLILATTTFPYDEPLLANSLL
TQCIHTFKNFHVDDFRPLLNDDPVESIAKVTLGRIFYRLCGCDYLQSGPR
KPIALHTEVSSLLQHAAYLQDNSTEVLYWKIISLDRDLDQYLNKSSKPPL
KTLDAIRRELDIFQYKVDSLEEDFRSNNSRFQKFIALFQISTVSWKLFKM
YLIYYDTADSLLKVIHYSKVIISLIVNNFHAKSEFFNRHPMVMQTITRVV
SFISFYQIFVESAAVKQLLVDLTELTANLPTIFGSKLDKLVYLTERLSKL
KLLWDKVQLLDSGDSFYHPVFKILQNDIKIIELKNDEMFSLIKGLGSLVP
LNSDFRTIVEEFQSEYNISDILS
3D structure
PDB6gys Architecture of the CBF3-centromere complex of the budding yeast kinetochore.
ChainC
Resolution4.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna C P13 K21 V22 K23 C24 R273 K368 P8 K16 V17 K18 C19 R266 K351
BS02 dna C K35 R36 L275 L276 Y325 P366 K368 T369 A372 K30 R31 L268 L269 Y318 P349 K351 T352 A355
BS03 ZN C C30 N32 C25 N27
BS04 ZN C C30 C33 C25 C28
Gene Ontology
Molecular Function
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0008301 DNA binding, bending
GO:0019237 centromeric DNA binding
GO:0042802 identical protein binding
GO:0046872 metal ion binding
Biological Process
GO:0000921 septin ring assembly
GO:0006355 regulation of DNA-templated transcription
GO:0006357 regulation of transcription by RNA polymerase II
GO:0007094 mitotic spindle assembly checkpoint signaling
GO:0051382 kinetochore assembly
Cellular Component
GO:0000775 chromosome, centromeric region
GO:0000776 kinetochore
GO:0005634 nucleus
GO:0005694 chromosome
GO:0031518 CBF3 complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6gys, PDBe:6gys, PDBj:6gys
PDBsum6gys
PubMed30478265
UniProtP40969|CBF3B_YEAST Centromere DNA-binding protein complex CBF3 subunit B (Gene Name=CEP3)

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