Structure of PDB 6gd3 Chain C

Receptor sequence
>6gd3C (length=84) Species: 9606 (Homo sapiens) [Search protein sequence]
GAMGWCIFIYNLGQDADEGILWQMFGPFGAVTNVKVIRDFNTNKCKGFGF
VTMTNYEEAAMAIASLNGYRLGDKILQVSFKTNK
3D structure
PDB6gd3 HuR biological function involves RRM3-mediated dimerization and RNA binding by all three RRMs.
ChainC
Resolution1.35 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna C F247 Y249 K274 K285 F287 F289 K313 Q316 K320 T321 K323 F8 Y10 K35 K46 F48 F50 K74 Q77 K81 T82 K84 PDBbind-CN: Kd=155.8uM
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding

View graph for
Molecular Function
External links
PDB RCSB:6gd3, PDBe:6gd3, PDBj:6gd3
PDBsum6gd3
PubMed30418581
UniProtQ15717|ELAV1_HUMAN ELAV-like protein 1 (Gene Name=ELAVL1)

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