Structure of PDB 6fuw Chain C

Receptor sequence
>6fuwC (length=114) Species: 9606 (Homo sapiens) [Search protein sequence]
MQEIIASVDHIKFDLEIAVEQQLGAQPLPFPGMKSGAAVCEFFLKAACGK
GGMCPFRHISGEKTVVCKHWLRGLCKKGDQCEFLHEYDMTKMPECYFYSK
FGECSNKECPFLHI
3D structure
PDB6fuw Structural basis of AAUAAA polyadenylation signal recognition by the human CPSF complex.
ChainC
Resolution3.07 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna C K69 H70 R73 K77 K78 F84 F98 S106 N107 F112 K68 H69 R72 K76 K77 F83 F97 S105 N106 F111
BS02 ZN C C41 C55 H59 C40 C54 H58
BS03 ZN C C68 C76 C82 H86 C67 C75 C81 H85
BS04 ZN C C96 C105 C110 H114 C95 C104 C109 H113
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:6fuw, PDBe:6fuw, PDBj:6fuw
PDBsum6fuw
PubMed29358758
UniProtO95639|CPSF4_HUMAN Cleavage and polyadenylation specificity factor subunit 4 (Gene Name=CPSF4)

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