Structure of PDB 6fhh Chain C

Receptor sequence
>6fhhC (length=725) Species: 1129347 (Influenza A virus (A/little yellow-shouldered bat/Guatemala/060/2010(H17N10))) [Search protein sequence]
SGMERIKELMEMVKNSRMREILTTTSVDHMAVIKKYTSGRQEKNPALRMK
WMMAMKYPISASSRIREMIPEKDEDGNTLWTNTKDAGSNRVLVSPNAVTW
WNRAGPVSDVVHYPRVYKMYFDRLERLTHGTFGPVKFYNQVKVRKRVDIN
PGHKDLTSREAQEVIMEVVFPNEVGARTLSSDAQLTITKEKKEELKNCKI
SPIMVAYMLERELVRRTRFLPIAGATSSTYVEVLHLTQGTCWEQQYTPGG
EAENDDLDQTLIIASRNIVRRSIVAIDPLASLLSMCHTTSISSEPLVEIL
RSNPTDEQAVNICKAALGIRINNSFSFGGYNFKRVKGSSQRTEKAVLTGN
LQTLTMTIFEGYEEFNVSGKRASAVLKKGAQRLIQAIIGGRTLEDILNLM
ITLMVFSQEEKMLKAVRGDLNFNPMYQLLRHFQKDSSTLLKNWGTEEIDP
IMGIAGIMPDGTINKTQTLMGVRLSQIRVNIDKYLRVRNEKGELLISPEE
VSEAQGQEKLPINYNSSLMWEVNGPESILTNTYHWIIKNWELLKTQWMTD
PTVLYNRIEFEPFQTLIPKGNRAIYSGFTRTLFQQMRDVEGTFDSIQIIK
LLPFSAHPPSLGRTQFSSFTLNIRGAPLRLLIRGNSQVFNYNQMENVIIV
LGKSVGSPERSILTESSSIESAVLRGFLILGKANSKYGPVLTIGELDKLG
RGEKANVLIGQGDTVLVMKRKRDSS
3D structure
PDB6fhh Towards New Anti-Influenza Therapeutics: Structure-Activity Relationships in the Interaction between Heterotrimeric Influenza Polymerase and Pol II C-terminal domain
ChainC
Resolution2.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 rna C S36 G37 R38 E40 R46 W49 S38 G39 R40 E42 R48 W51
Gene Ontology
Biological Process
GO:0006351 DNA-templated transcription
GO:0006370 7-methylguanosine mRNA capping
GO:0019083 viral transcription
GO:0039523 symbiont-mediated suppression of host mRNA transcription via inhibition of RNA polymerase II activity
GO:0075526 cap snatching
Cellular Component
GO:0033650 host cell mitochondrion
GO:0042025 host cell nucleus
GO:0044423 virion component

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:6fhh, PDBe:6fhh, PDBj:6fhh
PDBsum6fhh
PubMed
UniProtH6QM90

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