Structure of PDB 6f1c Chain C

Receptor sequence
>6f1cC (length=287) Species: 9606 (Homo sapiens) [Search protein sequence]
IPQKLFGEVTSPLFPKPYPNNFETTTVITVPTGYRVKLVFQQFDLEPSEG
CFYDYVKISADKKSLGRFCGQLGSPLGNPPGKKEFMSQGNKMLLTFHTDF
SNEENGTIMFYKGFLAYYQAVDLDECASRSKSGEEDPQPQCQHLCHNYVG
GYFCSCRPGYELQEDTHSCQAECSSELYTEASGYISSLEYPRSYPPDLRC
NYSIRVERGLTLHLKFLEPFDIDDHQQVHCPYDQLQIYANGKNIGEFCGK
QRPPDLDTSSNAVDLLFFTDESGDSRGWKLRYTTEII
3D structure
PDB6f1c Structure of the C1r-C1s interaction of the C1 complex of complement activation.
ChainC
Resolution4.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.21.41: complement subcomponent C1r.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA C D57 T101 D102 S104 N105 D54 T98 D99 S101 N102
BS02 CA C D125 L126 E128 Y151 G153 G154 D122 L123 E125 Y148 G150 G151
BS03 CA C Y197 D226 D236 D273 S275 Y194 D223 D233 D270 S272
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding

View graph for
Molecular Function
External links
PDB RCSB:6f1c, PDBe:6f1c, PDBj:6f1c
PDBsum6f1c
PubMed29311313
UniProtP00736|C1R_HUMAN Complement C1r subcomponent (Gene Name=C1R)

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