Structure of PDB 6exh Chain C

Receptor sequence
>6exhC (length=353) Species: 239 (Flavobacterium sp.) [Search protein sequence]
TSLTLEIPTSPLIIKITQQERNILSNVGNLLVKAFGNYENPDYIASLHLH
AFQLLPERITRILSQFGSDFSAEQYGAIVFQGLIEVDQDDLGPTPPNWQG
ADYGKLNKYGFICSLLHGAVPSKPVQYYAQRKGGGLLHAVIPDEKMAATQ
TGSGSKTDLFVHTEDAFLSNQADFLSFLYLRNEERVPSTLYSIRSHGKMN
PVMKKLFEPIYQCPKDANYANSGPTASVLYGNRELPFIRFDAAEQIFNEN
AGQTSEALGNLMDFWDEAKTLINSDYIPNSGDLIFVNNHLCAHGRSAFIA
GQRIENGEIIKCERRQMLRMMSKTSLIHIRSVTRTDDPYFIMEEHLGKIF
DLD
3D structure
PDB6exh Structural Studies based on two Lysine Dioxygenases with Distinct Regioselectivity Brings Insights Into Enzyme Specificity within the Clavaminate Synthase-Like Family.
ChainC
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.14.11.-
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 FE C H176 E178 H312 H162 E164 H293
BS02 LYO C Q144 Q164 T165 G166 H176 N232 R338 Q130 Q150 T151 G152 H162 N218 R319
Gene Ontology
Molecular Function
GO:0016706 2-oxoglutarate-dependent dioxygenase activity
GO:0046872 metal ion binding
GO:0051213 dioxygenase activity

View graph for
Molecular Function
External links
PDB RCSB:6exh, PDBe:6exh, PDBj:6exh
PDBsum6exh
PubMed30410048
UniProtJ3BZS6|LYS4O_FLASC L-lysine 4-hydroxylase (Gene Name=PMI10_03368)

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