Structure of PDB 6evk Chain C

Receptor sequence
>6evkC (length=727) Species: 1129347 (Influenza A virus (A/little yellow-shouldered bat/Guatemala/060/2010(H17N10))) [Search protein sequence]
SGMERIKELMEMVKNSRMREILTTTSVDHMAVIKKYTSGRQEKNPALRMK
WMMAMKYPISASSRIREMIPEKDEDGNTLWTNTKDAGSNRVLVSPNAVTW
WNRAGPVSDVVHYPRVYKMYFDRLERLTHGTFGPVKFYNQVKVRKRVDIN
PGHKDLTSREAQEVIMEVVFPNEVGARTLSSDAQLTITKEKKEELKNCKI
SPIMVAYMLERELVRRTRFLPIAGATSSTYVEVLHLTQGTCWEQQYTPGG
EAENDDLDQTLIIASRNIVRRSIVAIDPLASLLSMCHTTSISSEPLVEIL
RSNPTDEQAVNICKAALGIRINSFSFGGYNFKRVKGSSQRTEKAVLTGNL
QTLTMTIFEGYEEFNVSGKRASAVLKKGAQRLIQAIIGGRTLEDILNLMI
TLMVFSQEEKMLKAVRGDLNFVNQRLNPMYQLLRHFQKDSSTLLKNWGTE
EIDPIMGIAGIMPDGTINKTQTLMGVRLSQRVNIDKYLRVRNEKGELLIS
PEEVSEAQGQEKLPINYNSSLMWEVNGPESILTNTYHWIIKNWELLKTQW
MTDPTVLYNRIEFEPFQTLIPKGNRAIYSGFTRTLFQQMRDVEGTFDSIQ
IIKLLPFSAHPPSLGRTQFSSFTLNIRGAPLRLLIRGNSQVFNYNQMENV
IIVLGKSVGSPERSILTESSSIESAVLRGFLILGKANSKYGPVLTIGELD
KLGRGEKANVLIGQGDTVLVMKRKRDS
3D structure
PDB6evk Capped RNA primer binding to influenza polymerase and implications for the mechanism of cap-binding inhibitors.
ChainC
Resolution2.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna C G37 R38 E40 R46 W49 G39 R40 E42 R48 W51
BS02 MGP C F323 R339 T355 F357 E361 F363 K376 F404 Q406 N429 M431 F324 R340 T356 F358 E362 F364 K377 F405 Q407 N427 M429
BS03 PO4 C E662 I666 E648 I652
Gene Ontology
Biological Process
GO:0006351 DNA-templated transcription
GO:0006370 7-methylguanosine mRNA capping
GO:0019083 viral transcription
GO:0039523 symbiont-mediated suppression of host mRNA transcription via inhibition of RNA polymerase II activity
GO:0075526 cap snatching
Cellular Component
GO:0033650 host cell mitochondrion
GO:0042025 host cell nucleus
GO:0044423 virion component

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6evk, PDBe:6evk, PDBj:6evk
PDBsum6evk
PubMed29202182
UniProtH6QM90

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