Structure of PDB 6evj Chain C

Receptor sequence
>6evjC (length=748) Species: 1129347 (Influenza A virus (A/little yellow-shouldered bat/Guatemala/060/2010(H17N10))) [Search protein sequence]
GMERIKELMEMVKNSRMREILTTTSVDHMAVIKKYTSGRQEKNPALRMKW
MMAMKYPISASSRIREMIPEKDEDGNTLWTNTKDAGSNRVLVSPNAVTWW
NRAGPVSDVVHYPRVYKMYFDRLERLTHGTFGPVKFYNQVKVRKRVDINP
GHKDLTSREAQEVIMEVVFPNEVGARTLSSDAQLTITKEKKEELKNCKIS
PIMVAYMLERELVRRTRFLPIAGATSSTYVEVLHLTQGTCWEQQYTPGGE
AENDDLDQTLIIASRNIVRRSIVAIDPLASLLSMCHTTSISSEPLVEILR
SNPTDEQAVNICKAALGIRINNSFSFGGYNFKRVKGSSQRTEKAVLTGNL
QTLTMTIFEGYEEFNVSGKRASAVLKKGAQRLIQAIIGGRTLEDILNLMI
TLMVFSQEEKMLKAVRGDLNFVNRANQRLNPMYQLLRHFQKDSSTLLKNW
GTEEIDPIMGIAGIMPDGTINKTQTLMGVRLSQGGVDEYSFNERIRVNID
KYLRVRNEKGELLISPEEVSEAQGQEKLPINYNSSLMWEVNGPESILTNT
YHWIIKNWELLKTQWMTDPTVLYNRIEFEPFQTLIPKGNRAIYSGFTRTL
FQQMRDVEGTFDSIQIIKLLPFSAHPPSLGRTQFSSFTLNIRGAPLRLLI
RGNSQVFNYNQMENVIIVLGKSVGSPSILTESSSIESAVLRGFLILGKAN
SKYGPVLTIGELDKLGRGEKANVLIGQGDTVLVMKRKRDSSILTDSQT
3D structure
PDB6evj Capped RNA primer binding to influenza polymerase and implications for the mechanism of cap-binding inhibitors.
ChainC
Resolution3.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna C R38 E40 R46 W49 R39 E41 R47 W50
BS02 rna C I260 R264 D304 E305 Q306 F323 F357 E361 K376 F404 L428 N429 Y432 S519 A521 I261 R265 D305 E306 Q307 F324 F358 E362 K377 F405 L429 N430 Y433 S520 A522
Gene Ontology
Biological Process
GO:0006351 DNA-templated transcription
GO:0006370 7-methylguanosine mRNA capping
GO:0019083 viral transcription
GO:0039523 symbiont-mediated suppression of host mRNA transcription via inhibition of RNA polymerase II activity
GO:0075526 cap snatching
Cellular Component
GO:0033650 host cell mitochondrion
GO:0042025 host cell nucleus
GO:0044423 virion component

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6evj, PDBe:6evj, PDBj:6evj
PDBsum6evj
PubMed29202182
UniProtH6QM90

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