Structure of PDB 6dzs Chain C

Receptor sequence
>6dzsC (length=428) Species: 1122247 (Mycolicibacterium hassiacum DSM 44199) [Search protein sequence]
KPIGVAVLGLGNVGSEVVRIIDESATDLAARIGAPLQLRGIGVRRVSADR
GVPVELLTDNIEELVSRDDVDIVVELMGPVEPARKAILTALEQGKSVVTA
NKALMSVSTGELAQAAEAAHVDLYFEAAVAGAIPVIRPLTQSLAGDTVTR
VAGIVNGTTNYILSAMDSTGADYGDALAEASALGYAEADPTADVEGYDAA
AKAAILASIAFHTRVTADDVYREGITKVTAADFASARALGCTIKLLAICE
RLTSDDGHQSVSARVYPALVPLTHPLAAVNGAFNAVVVEAEAAGRLMFYG
QGAGGAPTASAVMGDVVMAARNRVQGGRGPRESKYAKLPISPIGDIPTRY
YVSMRVADRPGVLAAVATEFGNRSVSIAEVRQEGIDDGARLVVVTHKATD
AALSETVKALASLDVVQSVDSVIRMEGT
3D structure
PDB6dzs Structure of mycobacterial homoserine dehydrogenase ThrA
ChainC
Resolution2.62 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.1.1.3: homoserine dehydrogenase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAP C G14 L15 G16 N17 V18 V48 R49 R50 I66 L81 M82 A105 K107 G309 T313 G9 L10 G11 N12 V13 V43 R44 R45 I61 L76 M77 A100 K102 G304 T308
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0004412 homoserine dehydrogenase activity
GO:0016491 oxidoreductase activity
GO:0050661 NADP binding
Biological Process
GO:0006520 amino acid metabolic process
GO:0009086 methionine biosynthetic process
GO:0009088 threonine biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:6dzs, PDBe:6dzs, PDBj:6dzs
PDBsum6dzs
PubMed
UniProtK5BJC9

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