Structure of PDB 6dfq Chain C

Receptor sequence

>6dfqC (length=200) Species: 10090 (Mus musculus) [Search protein sequence]

MEKVEQHESTLSVREGDSAVINCTYTDTASSYFPWYKQEAGKGLHFVIDI
RSNVDRKQSQRLIVLLDKKAKRFSLHITATQPEDSAIYFCAASPSYKLTF
GKGTLLTVTPNIQNPDPAVYQLRDSKSSDKSVCLFTDFDSQTNVSQSKDS
DVYITDKCVLDMRSMDFKSNSAVAWSNKSDFACANAFNNSIIPEDTFFPS

3D structure

PDB

6dfq How C-terminal additions to insulin B-chain fragments create superagonists for T cells in mouse and human type 1 diabetes.

Chain

Resolution

2.6 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	CA	C	N120 P121	N114 P115

External links

PDB	RCSB:6dfq, PDBe:6dfq, PDBj:6dfq
PDBsum	6dfq
PubMed	30952805

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