Structure of PDB 6cxy Chain C

Receptor sequence
>6cxyC (length=213) Species: 9606 (Homo sapiens) [Search protein sequence]
DWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGV
FIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTD
QNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTI
LSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEG
LSTTATAVITVTD
3D structure
PDB6cxy Crystal Structure of Human E-cadherin bound by mouse monoclonal antibody Fab mAb-1_19A11
ChainC
Resolution2.2 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA C N102 N104 D134 D136 N143 D195 N102 N104 D134 D136 N143 D195
BS02 CA C E11 E69 D100 Q101 D103 D136 E11 E69 D100 Q101 D103 D136
BS03 CA C E11 D67 E69 D103 E11 D67 E69 D103
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
Biological Process
GO:0007155 cell adhesion
GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules
GO:0098609 cell-cell adhesion
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6cxy, PDBe:6cxy, PDBj:6cxy
PDBsum6cxy
PubMed
UniProtP12830|CADH1_HUMAN Cadherin-1 (Gene Name=CDH1)

[Back to BioLiP]