Structure of PDB 6cko Chain C |
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PDB | 6cko Structural and functional analysis of the DOT1L-AF10 complex reveals mechanistic insights into MLL-AF10-associated leukemogenesis. |
Chain | C |
Resolution | 2.0 Å |
3D structure |
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Enzyme Commision number |
2.1.1.360: [histone H3]-lysine(79) N-trimethyltransferase. |
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Site # |
Ligand |
Ligand chain |
Binding residues on receptor (original residue number in PDB) |
Binding residues on receptor (residue number reindexed from 1) |
Binding affinity |
BS01 |
ZN |
C |
H587 E591 |
H29 E33 |
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