Structure of PDB 6cju Chain C

Receptor sequence
>6cjuC (length=390) Species: 869211 (Spirochaeta thermophila DSM 6578) [Search protein sequence]
TYTLVWKVWILAVTLYYAIRIPLTLVFPSLFSPLLPLDILASLALIADIP
LDLLLAPSRLPDLLAALPLDLLVFALHLPSPLSLLSLVRLLKLISVQRSA
TRILSYRINPALLRLLSLVGFILLAAHGIACGWMSLQPPSENPAGTRYLS
AFYWTITTLTTIGYGDITPSTPTQTVYTIVIELLGAAMYGLVIGNIASLV
SKLDAAKLLHRERVERVTAFLSYKRISPELQRRIIEYFDYLWETRRGYEE
REVLKELPHPLRLAVAMEIHGDVIEKVPLFKGAGEEFIRDIILHLEPVIY
GPGEYIIRAGEMGSDVYFINRGSVEVLSADEKTRYAILSEGQFFGEMALI
LRAPRTATVRARAFCDLYRLDKETFDRILSRYPEIAAQIQ
3D structure
PDB6cju Ligand discrimination and gating in cyclic nucleotide-gated ion channels from apo and partial agonist-bound cryo-EM structures.
ChainC
Resolution3.35 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PGW C A209 L213 A187 L191
BS02 CMP C G367 E368 M369 R377 T378 A379 G345 E346 M347 R355 T356 A357
BS03 PGW C L32 Y170 L23 Y148
BS04 PGW C S102 L109 F143 G150 S157 L158 S80 L87 F121 G128 S135 L136
BS05 PGW C L137 V141 T182 L221 L115 V119 T160 L199
Gene Ontology
Molecular Function
GO:0005221 intracellularly cyclic nucleotide-activated monoatomic cation channel activity
GO:0044877 protein-containing complex binding
Biological Process
GO:0034220 monoatomic ion transmembrane transport
GO:0098655 monoatomic cation transmembrane transport
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6cju, PDBe:6cju, PDBj:6cju
PDBsum6cju
PubMed30028291
UniProtG0GA88

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