Structure of PDB 6cey Chain C

Receptor sequence
>6ceyC (length=289) Species: 1280 (Staphylococcus aureus) [Search protein sequence]
TNVKAMKYLIEHYFDNFKVDSIEIIGSGYDSVAYLVNNEYIFKTKFSYAK
EKAIYNFLNTNLETNVKIPNIEYSYISDELSILGYKEIKGTFLTPEIYST
MSEEEQNLLKRDIASFLRQMHGLDYTDISECTIDNKQNVLEEYILLRETI
YNDLTDIEKDYIESFMERLNATTVFEGKKCLCHNDFSCNHLLLDGNNRLT
GIIDFGDSGIIDEYCDFIYLLEDSEEEIGTNFGEDILRMYGNIDIEKAKE
YQDIVEEYYPIETIVYGIKNIKQEFIENGRKEIYKRTYK
3D structure
PDB6cey Plasticity of Aminoglycoside Binding to Antibiotic Kinase APH(2′′)-Ia.
ChainC
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.1.-
2.7.1.190: aminoglycoside 2''-phosphotransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GNP C I208 I224 K226 Y274 E276 I277 F281 H379 I392 D393 I25 I41 K43 Y85 E87 I88 F92 H190 I203 D204
BS02 MG C H379 D393 H190 D204
External links
PDB RCSB:6cey, PDBe:6cey, PDBj:6cey
PDBsum6cey
PubMed29661878
UniProtP0A0C1|AACA_STAAU Bifunctional AAC/APH (Gene Name=aacA-aphD)

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