Structure of PDB 6c99 Chain C

Receptor sequence
>6c99C (length=260) Species: 9606 (Homo sapiens) [Search protein sequence]
HLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAWVW
ENQVSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELSVPTA
KFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFS
CPHRLREHLERGRGNLEWKEPPSMRLKARPSSPGFSVLTCSAFSFYPPEL
QLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAG
LAQPLRVELE
3D structure
PDB6c99 Insight into small molecule binding to the neonatal Fc receptor by X-ray crystallography and 100 kHz magic-angle-spinning NMR.
ChainC
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 EQY C W29 Q34 G49 S230 W26 Q31 G46 S222 MOAD: Kd=2.4uM
External links
PDB RCSB:6c99, PDBe:6c99, PDBj:6c99
PDBsum6c99
PubMed29782488
UniProtP55899|FCGRN_HUMAN IgG receptor FcRn large subunit p51 (Gene Name=FCGRT)

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