Structure of PDB 6c8q Chain C

Receptor sequence
>6c8qC (length=265) Species: 226185 (Enterococcus faecalis V583) [Search protein sequence]
MTTLQEKIIQELGVLPTIDPKEEVRKSIDFLKAYLTKHPFLKTFVLGISG
GQDSTLAGRLAQLAMTEMREETGDMSYQFIAIRLPYGEQADEADAQAALA
FIQPDVSLRVDIKPAVDAMVGSLENAGVQISDFNKGNMKARQRMITQYAV
AGENAGAVIGTDHAAENVTAFFTKYGDGGADILPLFRLNKRQGKALLKEL
GAPEALYLKPLVADEVALGVTYDAIDDYLEGKKVSETDQQTIENWYKKGQ
HKRHLPITIFDDFWK
3D structure
PDB6c8q To be published
ChainC
Resolution2.583 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) D53 E166
Catalytic site (residue number reindexed from 1) D53 E166
Enzyme Commision number 6.3.1.5: NAD(+) synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAD C F133 N137 R141 F171 F172 T173 K174 A227 H261 K262 F133 N137 R141 F171 F172 T173 K174 A217 H251 K252
BS02 NAD C Y34 Y148 G156 D181 Y34 Y148 G156 D181
Gene Ontology
Molecular Function
GO:0003952 NAD+ synthase (glutamine-hydrolyzing) activity
GO:0004359 glutaminase activity
GO:0005524 ATP binding
GO:0008795 NAD+ synthase activity
GO:0016874 ligase activity
GO:0046872 metal ion binding
Biological Process
GO:0009435 NAD biosynthetic process
Cellular Component
GO:0005737 cytoplasm

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Biological Process
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Cellular Component
External links
PDB RCSB:6c8q, PDBe:6c8q, PDBj:6c8q
PDBsum6c8q
PubMed
UniProtQ830Y9|NADE_ENTFA NH(3)-dependent NAD(+) synthetase (Gene Name=nadE)

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