Structure of PDB 6b4h Chain C

Receptor sequence
>6b4hC (length=318) Species: 759272 (Thermochaetoides thermophila DSM 1495) [Search protein sequence]
GPHMRYVEIHRNLKGLRKYMAEQAKTNLKLKQRMGDMRREIRKSVGQLTT
GGMAANKDKQQKIKSILTEALSNQVESALVDPNNFVVEPRKPVEGATNND
PLLPSIFVYLINIFAKAAISQFINEAGARPETADPVGICVAAILSEPDFL
WRGASLIDILIAKFRIVCPVLFGYRGSEKTEQGRQRLGWWKESGQWISEQ
QHMDRMTGLGAGFAAISLRKFALSKKQNPYPPRFYWMAMAKIVNTPPAEI
SNTQCVVLKAMVQNYEAKFIEFYGSAAIAALRTALIDFPARAPHKSAAVN
SLEVLAQMLKRDTGLDLG
3D structure
PDB6b4h Structural and functional analysis of mRNA export regulation by the nuclear pore complex.
ChainC
Resolution2.17 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 IHP C H221 K225 R228 K327 K374 W401 H10 K14 R17 K116 K163 W190 PDBbind-CN: -logKd/Ki=8.52,Kd~3nM
BS02 IHP C S435 K436 K437 S224 K225 K226 PDBbind-CN: -logKd/Ki=8.52,Kd~3nM
Gene Ontology
Biological Process
GO:0016973 poly(A)+ mRNA export from nucleus
Cellular Component
GO:0005643 nuclear pore

View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6b4h, PDBe:6b4h, PDBj:6b4h
PDBsum6b4h
PubMed29899397
UniProtG0S7F3|GLE1_CHATD mRNA export factor GLE1 (Gene Name=GLE1)

[Back to BioLiP]