Structure of PDB 6azr Chain C

Receptor sequence
>6azrC (length=234) Species: 243274 (Thermotoga maritima MSB8) [Search protein sequence]
LKRIDRMKTEFIANISHELRAPLTAIKAYAETIYNSLGELDLSTLKEFLE
VIIDQSNHLENLLNELLDFSRLERKSLQINREKVDLCDLVESAVNAIKEF
ASSHNVNVLFESNVPCPVEAYIDPTRIRQVLLNLLNNGVKYSKKDAPDKY
VKVILDEKDGGVLIIVEDNGIGIPDHAKDRIFEQFYRVDSYEVPGTGLGL
AITKEIVELHGGRIWVESEVGKGSRFFVWIPKDR
3D structure
PDB6azr A pH-gated conformational switch regulates the phosphatase activity of bifunctional HisKA-family histidine kinases.
ChainC
Resolution3.628 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.13.3: histidine kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ANP C E308 N380 K383 Y384 D411 R430 V431 T442 G443 G445 L446 S470 F472 E65 N137 K140 Y141 D168 R187 V188 T196 G197 G199 L200 S224 F226
Gene Ontology
Molecular Function
GO:0000155 phosphorelay sensor kinase activity
GO:0016772 transferase activity, transferring phosphorus-containing groups
Biological Process
GO:0007165 signal transduction
GO:0016310 phosphorylation

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Molecular Function
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Biological Process
External links
PDB RCSB:6azr, PDBe:6azr, PDBj:6azr
PDBsum6azr
PubMed29235472
UniProtQ9WZV7

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