Structure of PDB 6akp Chain C

Receptor sequence
>6akpC (length=94) Species: 9606 (Homo sapiens) [Search protein sequence]
GPKPPYSYIALITMAIQNAPEKKITLNGIYQFIMDRFPFYRENKQGWQNS
IRHNLSLNECFVKVPRDKGSYWTLDPDSYNMFENGSFLRRRRRF
3D structure
PDB6akp Structural basis for DNA recognition by FOXC2.
ChainC
Resolution2.323 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna C L95 R121 S125 K132 W146 L26 R52 S56 K63 W72
BS02 MG C L124 S125 N127 F130 L55 S56 N58 F61
Gene Ontology
Molecular Function
GO:0003700 DNA-binding transcription factor activity
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:6akp, PDBe:6akp, PDBj:6akp
PDBsum6akp
PubMed30722065
UniProtQ99958|FOXC2_HUMAN Forkhead box protein C2 (Gene Name=FOXC2)

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