Structure of PDB 5zup Chain C

Receptor sequence
>5zupC (length=66) Species: 9606 (Homo sapiens) [Search protein sequence]
SHMEQRILKFLEELGEGKATTAHDLSGKLGTPKKEINRVLYSLAKKGKLQ
KEAGTPPLWKIAVSTQ
3D structure
PDB5zup Sequence preference and structural heterogeneity of BZ junctions.
ChainC
Resolution2.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.5.4.37: double-stranded RNA adenine deaminase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna C H159 G163 H23 G27
BS02 dna C K170 N173 R174 Y177 T191 P192 P193 K34 N37 R38 Y41 T55 P56 P57
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003726 double-stranded RNA adenosine deaminase activity

View graph for
Molecular Function
External links
PDB RCSB:5zup, PDBe:5zup, PDBj:5zup
PDBsum5zup
PubMed30184200
UniProtP55265|DSRAD_HUMAN Double-stranded RNA-specific adenosine deaminase (Gene Name=ADAR)

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