Structure of PDB 5z2m Chain C

Receptor sequence
>5z2mC (length=168) Species: 10090 (Mus musculus) [Search protein sequence]
KKVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKAADFLTKEVMVDDRLV
TMQIWDTAGLERFQSLGVAFYRGADCCVLVFDVTAPNTFKTLDSWRDEFL
IQASPRDPENFPFVVLGNKIDLENRQVATKRAQAWCYSKNNIPYFETSAK
EAINVEQAFQTIARNALK
3D structure
PDB5z2m A non-canonical GTPase interaction enables ORP1L-Rab7-RILP complex formation and late endosome positioning.
ChainC
Resolution2.142 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.5.2: small monomeric GTPase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GTP C G18 V19 G20 K21 T22 S23 F33 N35 D63 N125 K126 D128 L129 S155 A156 K157 G14 V15 G16 K17 T18 S19 F29 N31 D56 N118 K119 D121 L122 S148 A149 K150
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding

View graph for
Molecular Function
External links
PDB RCSB:5z2m, PDBe:5z2m, PDBj:5z2m
PDBsum5z2m
PubMed30012887
UniProtP51150|RAB7A_MOUSE Ras-related protein Rab-7a (Gene Name=Rab7a)

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