Structure of PDB 5yyf Chain C

Receptor sequence
>5yyfC (length=139) Species: 9606 (Homo sapiens) [Search protein sequence]
HMASSCAVQVKLELGHRAQVRKKPTVEGFTHDWMVFVRGPEHSNIQHFVE
KVVFHLHESFPRPKRVCKDPPYKVEESGYAGFILPIEVYFKNKEEPRKVR
FDYDLFLHLEGHPPVNHLRCEKLTFNNPTEDFRRKLLKA
3D structure
PDB5yyf Structure-guided development of YEATS domain inhibitors by targeting pi-pi-pi stacking.
ChainC
Resolution1.903 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide C H0 E109 H1 E110
BS02 peptide C S58 A79 G80 F81 D103 F105 L106 H107 L108 H111 S59 A80 G81 F82 D104 F106 L107 H108 L109 H112
BS03 FOA C F28 S58 F59 S76 G77 Y78 F29 S59 F60 S77 G78 Y79
Gene Ontology
Biological Process
GO:0006355 regulation of DNA-templated transcription

View graph for
Biological Process
External links
PDB RCSB:5yyf, PDBe:5yyf, PDBj:5yyf
PDBsum5yyf
PubMed30374167
UniProtP42568|AF9_HUMAN Protein AF-9 (Gene Name=MLLT3)

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