Structure of PDB 5y4q Chain C

Receptor sequence
>5y4qC (length=272) Species: 353153 (Trypanosoma cruzi strain CL Brener) [Search protein sequence]
GWFREENDQPGQAMSLRVEKVLYDAPTKFQHLTIFESDPKGPWGTVMALD
GCIQVTDYDEFVYHEVLGHTSLCSHPKPERVLIIGGGDGGVLREVLRHGT
VEHCDLVDIDGEVMEQSKQHFPQISRSLADPRATVRVGDGLAFVRQTPDN
TYDVVIIDTTAFYKDVLRILKPDGICCNQGESIWLDLELIEKMSRFIRET
GFASVQYALMHVPTYPCGSIGTLVCSKKAGVDVTKPLRPVEDMPFAKDLK
YYDSEMHKASFALPRFARHINN
3D structure
PDB5y4q Discovering a hidden allosteric binding site by combining molecular simulations and X-ray crystallography
ChainC
Resolution2.07 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.5.1.16: spermidine synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 S4M C Q40 L59 Q64 H74 G95 D98 D118 I119 V123 D149 G150 D168 T169 Q30 L49 Q54 H64 G85 D88 D108 I109 V113 D139 G140 D158 T159
BS02 8OF C E14 W53 I63 Q64 Y73 T236 Y237 P238 E5 W43 I53 Q54 Y63 T214 Y215 P216
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0004766 spermidine synthase activity
GO:0016740 transferase activity
Biological Process
GO:0006596 polyamine biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:5y4q, PDBe:5y4q, PDBj:5y4q
PDBsum5y4q
PubMed37521650
UniProtQ4DA73

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