Structure of PDB 5wvo Chain C

Receptor sequence
>5wvoC (length=232) Species: 9606 (Homo sapiens) [Search protein sequence]
CIQCGLKYGQHPPDAVDEPQMLTNEKLSIFDANESGFESYEALPQHKLTC
FSVYCKHGHLCPIDTGLIEKNIELFFSGSAKPIYDDDPSLEGGVNGKNLG
PINEWWITGFDGGEKALIGFSTSFAEYILMDPSPEYAPIFGLMQEKIYIS
KIVVEFLQSNSDSTYEDLINKIETTVPPSGLNLNRFTEDSLLRHAQFVVE
QVESYDEAGDSDEQPIFLTPCMRDLIKLAGVT
3D structure
PDB5wvo Structure of the Dnmt1 Reader Module Complexed with a Unique Two-Mono-Ubiquitin Mark on Histone H3 Reveals the Basis for DNA Methylation Maintenance
ChainC
Resolution1.997 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.1.1.37: DNA (cytosine-5-)-methyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide C I427 E428 N430 N462 E463 W464 W465 I466 T467 F469 Q517 Q560 S563 Y564 G568 D569 D571 E572 I68 E69 N71 N103 E104 W105 W106 I107 T108 F110 Q158 Q201 S204 Y205 G209 D210 D212 E213
BS02 ZN C C353 C356 C414 H418 C1 C4 C55 H59
External links
PDB RCSB:5wvo, PDBe:5wvo, PDBj:5wvo
PDBsum5wvo
PubMed29053958
UniProtP26358|DNMT1_HUMAN DNA (cytosine-5)-methyltransferase 1 (Gene Name=DNMT1)

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