Structure of PDB 5wmh Chain C

Receptor sequence
>5wmhC (length=401) Species: 3702 (Arabidopsis thaliana) [Search protein sequence]
DMSLSPRVQSLKPSKTMVITDLAATLVQSGVPVIRLAAGEPDFDTPKVVA
EAGINAIREGFTRYTLNAGITELREAICRKLKEENGLSYAPDQILVSNGA
KQSLLQAVLAVCSPGDEVIIPAPYWVSYTEQARLADATPVVIPTKISNNF
LLDPKDLESKLTEKSRLLILCSPSNPTGSVYPKSLLEEIARIIAKHPRLL
VLSDEIYEHIIYAPATHTSFASLPDMYERTLTVNGFSKAFAMTGWRLGYL
AGPKHIVAACSKLQGQVSSGASSIAQKAGVAALGLGKAGGETVAEMVKAY
RERRDFLVKSLGDIKGVKISEPQGAFYLFIDFSAYYGSEAEGFGLINDSS
SLALYFLDKFQVAMVPGDAFGDDSCIRISYATSLDVLQAAVEKIRKALEP
L
3D structure
PDB5wmh Structural basis for substrate recognition and inhibition of prephenate aminotransferase from Arabidopsis.
ChainC
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.6.1.1: aspartate transaminase.
2.6.1.78: aspartate--prephenate aminotransferase.
2.6.1.79: glutamate--prephenate aminotransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PLP C G167 A168 W193 D272 I274 Y275 S305 K306 R314 G99 A100 W125 D204 I206 Y207 S237 K238 R246
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity
GO:0008483 transaminase activity
GO:0030170 pyridoxal phosphate binding
GO:0033853 aspartate-prephenate aminotransferase activity
GO:0033854 glutamate-prephenate aminotransferase activity
Biological Process
GO:0006520 amino acid metabolic process
GO:0008652 amino acid biosynthetic process
GO:0009058 biosynthetic process
GO:0009094 L-phenylalanine biosynthetic process
GO:0009095 aromatic amino acid family biosynthetic process, prephenate pathway
GO:0009793 embryo development ending in seed dormancy
Cellular Component
GO:0005829 cytosol
GO:0009507 chloroplast
GO:0009570 chloroplast stroma

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5wmh, PDBe:5wmh, PDBj:5wmh
PDBsum5wmh
PubMed29405514
UniProtQ9SIE1|PAT_ARATH Bifunctional aspartate aminotransferase and glutamate/aspartate-prephenate aminotransferase (Gene Name=PAT)

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