Structure of PDB 5wgm Chain C

Receptor sequence
>5wgmC (length=361) Species: 7955 (Danio rerio) [Search protein sequence]
SNAGGSSPITGLVYDQRMMLHHNMWDSHHPELPQRISRIFSRHEELRLLS
RCHRIPARLATEEELALCHSSKHISIIKSSEHMKPRDLNRLGDEYNSIFI
SNESYTCALLAAGSCFNSAQAILTGQVRNAVAIVRPPGHHAEKDTACGFC
FFNTAALTARYAQSITRESLRVLIVDWDVHHGNGTQHIFEEDDSVLYISL
HRYEDGAFFPNSEDANYDKVGLGKGRGYNVNIPWNGGKMGDPEYMAAFHH
LVMPIAREFAPELVLVSAGFDAARGDPLGGFQVTPEGYAHLTHQLMSLAA
GRVLIILEGGYNLTSISESMSMCTSMLLGDSPPSLTPLKTSATVSINNVL
RAHAPFWSSLR
3D structure
PDB5wgm Unusual zinc-binding mode of HDAC6-selective hydroxamate inhibitors.
ChainC
Resolution1.75 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ZN C D612 H614 D705 D178 H180 D271
BS02 AH7 C P464 S531 G582 F583 H614 F643 D705 L712 Y745 P30 S97 G148 F149 H180 F209 D271 L278 Y311
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