Structure of PDB 5w7x Chain C

Receptor sequence
>5w7xC (length=102) Species: 9606 (Homo sapiens) [Search protein sequence]
GGFELQPRDGGPRVALAPGETVIGRGPLLGITDKRVSRRHAILEVAGGQL
RIKPIHTNPCFYQSSEKSQLLPLKPNLWCYLNPGDSFSLLVDKYIFRILS
IP
3D structure
PDB5w7x Characterization of the APLF FHA-XRCC1 phosphopeptide interaction and its structural and functional implications.
ChainC
Resolution2.005 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide C P14 L31 G32 P12 L29 G30
BS02 peptide C R27 G28 P29 I33 K36 S39 R40 H58 R25 G26 P27 I31 K34 S37 R38 H56
Gene Ontology
Molecular Function
GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity
GO:0008408 3'-5' exonuclease activity
Biological Process
GO:0006302 double-strand break repair

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Molecular Function
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Biological Process
External links
PDB RCSB:5w7x, PDBe:5w7x, PDBj:5w7x
PDBsum5w7x
PubMed29059378
UniProtQ8IW19|APLF_HUMAN Aprataxin and PNK-like factor (Gene Name=APLF)

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