Structure of PDB 5vx3 Chain C

Receptor sequence
>5vx3C (length=141) Species: 9606 (Homo sapiens) [Search protein sequence]
SMSQSNRELVVDFLSYKLSQKGYSWSQMAAVKQALREAGDEFELRYRRAF
SDLTSQLHITPGTAYQSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESV
DKEMQVLVSRIAAWMATYLNDHLEPWIQENGGWDTFVELYG
3D structure
PDB5vx3 Conversion of Bim-BH3 from Activator to Inhibitor of Bak through Structure-Based Design.
ChainC
Resolution1.945 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide C E96 F97 R100 Y101 F105 L108 L112 S122 Q125 V126 E129 N136 W137 G138 R139 Y195 E41 F42 R45 Y46 F50 L53 L57 S67 Q70 V71 E74 N81 W82 G83 R84 Y140
Gene Ontology
Biological Process
GO:0042981 regulation of apoptotic process

View graph for
Biological Process
External links
PDB RCSB:5vx3, PDBe:5vx3, PDBj:5vx3
PDBsum5vx3
PubMed29149594
UniProtQ07817|B2CL1_HUMAN Bcl-2-like protein 1 (Gene Name=BCL2L1)

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