Structure of PDB 5vwx Chain C

Receptor sequence
>5vwxC (length=148) Species: 9606 (Homo sapiens) [Search protein sequence]
MSEEQVAQDTEEVFRSYVFYRHQQEQEALQPSSTMGQVGRQLAIIGDDIN
RRYDSEFQTMLQHLQPTAENAYEYFTKIATSLFESGINWGRVVALLGFGY
RLALHVYQHGLTGFLGQVTRFVVDFMLHHSIARWIAQRGGWVAALNLG
3D structure
PDB5vwx Conversion of Bim-BH3 from Activator to Inhibitor of Bak through Structure-Based Design.
ChainC
Resolution2.489 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide C R42 I81 I85 N86 R88 Y89 E92 F93 M96 H99 I114 S117 L118 S121 N124 G126 R127 A130 R137 R21 I45 I49 N50 R52 Y53 E56 F57 M60 H63 I78 S81 L82 S85 N88 G90 R91 A94 R101
Gene Ontology
Biological Process
GO:0042981 regulation of apoptotic process

View graph for
Biological Process
External links
PDB RCSB:5vwx, PDBe:5vwx, PDBj:5vwx
PDBsum5vwx
PubMed29149594
UniProtQ16611|BAK_HUMAN Bcl-2 homologous antagonist/killer (Gene Name=BAK1)

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