Structure of PDB 5vvv Chain C

Receptor sequence
>5vvvC (length=423) Species: 9606 (Homo sapiens) [Search protein sequence]
HFLCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWR
EMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKL
DQVSQFGCRSFALLFDNIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGE
PETFLFCPTEYCGTFCYPNVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKE
IPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLK
GVLTNPNCEFEANYVAIHTLATWYKSNLYSPQMALKLALTEWLQEFSVTL
EDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSIEEWRSRAAKFEEMC
GLVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGCRSHSS
AQFLIEPWAFRGGLAGEFQRLLP
3D structure
PDB5vvv Structural insights into the substrate binding adaptability and specificity of human O-GlcNAcase.
ChainC
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.2.1.169: protein O-GlcNAcase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide C W645 W679 W377 W408
BS02 peptide C Y69 N175 F223 Y11 N117 F165
External links
PDB RCSB:5vvv, PDBe:5vvv, PDBj:5vvv
PDBsum5vvv
PubMed28939839
UniProtO60502|OGA_HUMAN Protein O-GlcNAcase (Gene Name=OGA)

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