Structure of PDB 5vt6 Chain C

Receptor sequence
>5vt6C (length=240) Species: 320372 (Burkholderia pseudomallei 1710b) [Search protein sequence]
KRVAFVTGGMGGLGAAISRRLHDAGMAVAVSHSERNDHVSTWLMHERDAG
RDFKAYAVDVADFESCERCAEKVLADFGKVDVLINNAGITRDATFMKMTK
GDWDAVMRTDLDAMFNVTKQFIAGMVERRFGRIVNIGSVNGSRGAFGQAN
YASAKAGIHGFTKTLALETAKRGITVNTVSPGYLATVPQDVLEAKILPQI
PVGRLGRPDEVAALIAFLCSDDAGFVTGADLAINGGMHMS
3D structure
PDB5vt6 Crystal structure of Acetoacetyl-CoA Reductase from Burkholderia pseudomallei 1710b complexed with NADP
ChainC
Resolution1.7 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) G15 D105 S141 Y154 K158
Catalytic site (residue number reindexed from 1) G12 D102 S138 Y151 K155
Enzyme Commision number 1.1.1.36: acetoacetyl-CoA reductase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAP C G11 G14 G15 L16 H35 S36 N39 V61 D62 V63 N89 A90 G91 I92 I139 Y154 K158 P184 Y186 L187 G8 G11 G12 L13 H32 S33 N36 V58 D59 V60 N86 A87 G88 I89 I136 Y151 K155 P181 Y183 L184
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0016491 oxidoreductase activity
GO:0018454 acetoacetyl-CoA reductase activity
Biological Process
GO:0042619 poly-hydroxybutyrate biosynthetic process
Cellular Component
GO:0005737 cytoplasm

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Cellular Component
External links
PDB RCSB:5vt6, PDBe:5vt6, PDBj:5vt6
PDBsum5vt6
PubMed
UniProtQ3JJT1

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