Structure of PDB 5vay Chain C

Receptor sequence
>5vayC (length=139) Species: 9606 (Homo sapiens) [Search protein sequence]
YDNREIVMKYIHYKLSQRGYEWDASEVVHLTLRQAGDDFSRRYRRDFAEM
SSQLHLTPFTARGRFATVVEELFRDGVNWGRIVAFFEFGGVMCVESVNRE
MSPLVDNIALWMTEYLNRHLHTWIQDNGGWDAFVELYGP
3D structure
PDB5vay Bcl-2 complex with Beclin 1 pT108 BH3 domain
ChainC
Resolution1.804 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide C D111 F112 D46 F47
BS02 peptide C A100 F104 R107 Y108 F112 M115 Q118 H120 V133 E136 L137 D140 N143 G145 R146 F153 Y202 A35 F39 R42 Y43 F47 M50 Q53 H55 V68 E71 L72 D75 N78 G80 R81 F88 Y137
Gene Ontology
Biological Process
GO:0042981 regulation of apoptotic process

View graph for
Biological Process
External links
PDB RCSB:5vay, PDBe:5vay, PDBj:5vay
PDBsum5vay
PubMed
UniProtP10415|BCL2_HUMAN Apoptosis regulator Bcl-2 (Gene Name=BCL2);
Q07817|B2CL1_HUMAN Bcl-2-like protein 1 (Gene Name=BCL2L1)

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