Structure of PDB 5vau Chain C

Receptor sequence
>5vauC (length=139) Species: 9606 (Homo sapiens) [Search protein sequence]
YDNREIVMKYIHYKLSQRGYEWDASEVVHLTLRQAGDDFSRRYRRDFAEM
SSQLHLTPFTARGRFATVVEELFRDGVNWGRIVAFFEFGGVMCVESVNRE
MSPLVDNIALWMTEYLNRHLHTWIQDNGGWDAFVELYGP
3D structure
PDB5vau Bcl-2 complex with Beclin 1 BH3 domain
ChainC
Resolution1.754 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide C D111 F112 D46 F47
BS02 peptide C A100 D103 F104 R107 Y108 F112 M115 Q118 L119 V133 E136 L137 D140 N143 G145 R146 F153 Y202 A35 D38 F39 R42 Y43 F47 M50 Q53 L54 V68 E71 L72 D75 N78 G80 R81 F88 Y137
Gene Ontology
Biological Process
GO:0042981 regulation of apoptotic process

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Biological Process
External links
PDB RCSB:5vau, PDBe:5vau, PDBj:5vau
PDBsum5vau
PubMed
UniProtP10415|BCL2_HUMAN Apoptosis regulator Bcl-2 (Gene Name=BCL2)

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