Structure of PDB 5uw4 Chain C

Receptor sequence
>5uw4C (length=638) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
SRDLQNHLLFETATEVANRVGGIYSVLKSKAPITVAQYKDHYHLIGPLNK
ATYQNEVDILDWKKPEAFSDEMRPVQHALQTMESRGVHFVYGRWLIEGAP
KVILFDLDSVRGYSNEWKGDLWSLVGIPSPENDFETNDAILLGYTVAWFL
GEVAHLDSQHAIVAHFHQWLAGVALPLCRKRRIDVVTIFTTHATLLGRYL
CASGSFDFYNCLESVDVDHEAGRFGIYHRYCIERAAAHSADVFTTVSQIT
AFEAEHLLKRKPDGILPNGLNVIKFQAFHEFQNLHALKKEKINDFVRGHF
HGCFDFDLDNTLYFFIAGRYEYKNKGADMFIEALARLNYRLKVSGSKKTV
VAFIVMPAKNNSFTVEALKGQAEVRALENTVHEVTTSIGKRIFDHAIRYP
HNGLTTELPTDLGELLKSSDKVMLKRRILALRRPEGQLPPIVTHNMVDDA
NDLILNKIRQVQLFNSPSDRVKMIFHPEFLNANNPILGLDYDEFVRGCHL
GVFPSYYEPWGYTPAECTVMGVPSITTNVSGFGSYMEDLIETNQAKDYGI
YIVDRRFKAPDESVEQLVDYMEEFVKKTRRQRINQRNRTERLSDLLDWKR
MGLEYVKARQLALRRGYPDQFRELVGEELNDSNMDALA
3D structure
PDB5uw4 Activated state yeast Glycogen Synthase in complex with UDP glucosamine
ChainC
Resolution2.98 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.4.1.11: glycogen(starch) synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GCS C H193 R199 N269 E509 P510 W511 G512 H192 R198 N268 E508 P509 W510 G511
BS02 UDP C R20 G22 G23 R320 K326 F480 Y492 Y513 T514 E517 R19 G21 G22 R319 K325 F479 Y491 Y512 T513 E516
BS03 G6P C Q283 H286 K290 H500 R580 R583 I584 R587 Q282 H285 K289 H499 R579 R582 I583 R586
Gene Ontology
Molecular Function
GO:0004373 alpha-1,4-glucan glucosyltransferase (UDP-glucose donor) activity
GO:0005515 protein binding
GO:0016757 glycosyltransferase activity
GO:0042802 identical protein binding
GO:2001069 glycogen binding
Biological Process
GO:0005978 glycogen biosynthetic process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0042587 glycogen granule

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5uw4, PDBe:5uw4, PDBj:5uw4
PDBsum5uw4
PubMed
UniProtP27472|GYS2_YEAST Glycogen [starch] synthase isoform 2 (Gene Name=GSY2)

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